TABLE 1.
Detection and sequencing of poliovirus in 155 Pakistan stool samples using nanopore sequencing compared with cell culturea
Culture result | Nanopore sequencing results (no. of samples) |
||||||||
---|---|---|---|---|---|---|---|---|---|
Sabin 1 | Sabin 2 | VDPV2 | Sabin 3 | Wild-type 1 | Sabin 1 + 3 | Sabin 1 + Sabin 3 + VDPV2 | Wild-type 1 + Sabin 1 | Negative | |
Sabin 1 | 6 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 1 |
Sabin 2 | 0 | 28 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
VDPV2 | 0 | 1 | 9 | 0 | 0 | 0 | 0 | 0 | 1 |
Sabin 3 | 0 | 0 | 0 | 24 | 1 | 5 | 1 | 0 | 2 |
Wild-type 1 | 0 | 0 | 0 | 0 | 29 | 1 | 0 | 1 | 2 |
Sabin 1+3 | 0 | 0 | 0 | 2 | 0 | 32 | 0 | 0 | 4 |
Concordant results by nanopore sequencing and culture are highlighted in bold.