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. 2020 Aug 24;58(9):e00284-20. doi: 10.1128/JCM.00284-20

FIG 3.

FIG 3

Alignment of amino acid sequences at the cleavage sites of proteases 2Apro and 3Cpro of 27 representative EV-D68 strains. Two amino acid substitutions, T860N in 2Apro at the position between VP1 and 2A and S1108G in 3Cpro between 2B and 2C, were observed only in the subclade B1 strains from the 2014 outbreak. The gaps are indicated by dashes and the conserved amino acid residues by dots. Asterisks indicate EV-D68 strains from the Lower Hudson Valley.