TABLE 4.
Study and vaccine |
Strain | Concordance correlation coefficientb (95% CI) |
Precision coefficientc
(95% CI) |
Accuracy coefficientd
(95% CI) |
---|---|---|---|---|
1 | ||||
TIVc | A/H1N1 | 0.93 (0.92 to 0.93) | 0.96 (0.96 to 0.96) | 0.97 (0.96 to 0.97) |
A/H3N2 | 0.97 (0.97 to 0.97) | 0.98 (0.98 to 0.98) | 0.99 (0.99 to 0.99) | |
B | 0.82 (0.80 to 0.83) | 0.94 (0.93 to 0.94) | 0.87 (0.86 to 0.88) | |
TIVe | A/H1N1 | 0.74 (0.70 to 0.77) | 0.85 (0.83 to 0.88) | 0.87 (0.84 to 0.89) |
A/H3N2 | 0.95 (0.95 to 0.96) | 0.97 (0.97 to 0.98) | 0.98 (0.97 to 0.98) | |
B | 0.82 (0.79 to 0.84) | 0.94 (0.93 to 0.95) | 0.87 (0.85 to 0.88) | |
2 | ||||
aQIV | A/H3N2 | 0.87 (0.86 to 0.89) | 0.90 (0.89 to 0.91) | 0.96 (0.96 to 0.97) |
B | 0.86 (0.85 to 0.88) | 0.87 (0.86 to 0.88) | 0.99 (0.99 to 0.99) | |
QIV | A/H3N2 | 0.89 (0.88 to 0.90) | 0.92 (0.91 to 0.93) | 0.97 (0.96 to 0.97) |
B | 0.85 (0.83 to 0.86) | 0.85 (0.84 to 0.87) | 0.99 (0.99 to 0.99) |
Abbreviations: aQIV, adjuvanted quadrivalent influenza vaccine; CI, confidence interval; QIV, nonadjuvanted quadrivalent influenza vaccine; TIVc, cell-derived trivalent influenza vaccine; TIVe, egg-derived trivalent influenza vaccine.
The concordance correlation coefficient is a measure of agreement along the identity line, calculated as precision multiplied by accuracy.
The precision component is equivalent to the Pearson correlation coefficient, a measure of the deviation from the best-fitted line.
Accuracy is a correction factor that measures how far the best-fitted line deviates from the line of identity.