TABLE 4.
Clinical investigation of cases rejected for FilmArray ME panel testing due to normal CSF WBC counts but positive with a conventional test
| Conventional test result | Clinical comorbidity(ies)a | Treatment decision | Impacts of ME panel rejection |
|---|---|---|---|
| HHV-6 detected | Lymphoma, status post-BMT | Foscarnet started | Diagnosis delayed 18 h,b treatment delayed 22 hb |
| HHV-6 detected | MDS, status post-BMT | Foscarnet started | Diagnosis delayed 133 h,b treatment delayed 136 hb |
| CMV detected | CNS vasculitis, on immunosuppressive therapy | Ganciclovir started | Diagnosis delayed 44 h,b treatment delayed 46 hb |
| VZV detected | Status post-liver transplant | Acyclovir continued | Diagnosis delayed 32 h,b no treatment delay |
BMT, bone marrow transplant; MDS, myelodysplastic syndrome; CNS, central nervous system.
Assumes that the Film Array ME panel would have detected the target detected by the conventional assay.