TABLE 5.
Positive FilmArray ME panel results and assessment for false positivity based on conventional test results and clinical adjudicationa
| ME panel target | No. of specimens that tested positive (%) | No. of false-positive specimens (%) |
|---|---|---|
| Viral targets (n = 35) | ||
| EV | 8 (16.3) | 0 |
| HPeV | 0 | NA |
| HSV-1 | 4 (8.2) | 0 |
| HSV-2 | 6 (12.2) | 0 |
| VZV | 9 (18.4) | 0 |
| CMV | 0 | NA |
| HHV-6 | 8 (16.3) | 0 |
| Nonviral targets (n = 14) | ||
| E. coli | 1 (2.0) | 0 |
| H. influenzae | 2 (4.1) | 1 (2.0) |
| N. meningitidis | 0 | NA |
| S. pneumoniae | 3 (6.1) | 0 |
| S. agalactiae | 5 (10.2) | 2 (4.1) |
| L. monocytogenes | 0 | NA |
| C. neoformans/C. gattii | 3 (6.1) | 1 (2.0) |
| All targetsb | 49 | 4c (8.2) |
a
The reference result was based on concurrent conventional test results and clinical adjudication. NA, not applicable.
b
Two targets were excluded because they did not have concurrent conventional test results.
c
All false-positive results had discrepant ME panel and conventional test results. None of the discrepant ME panel results were clinically adjudicated to represent true-positive results.