TABLE 1.
Demographics of patients with K. aerogenes and Enterobacter cloacae complex (Ecc) bloodstream infections at Duke University from 2002 to 2015a
| Clinical characteristics | K. aerogenes (n = 46) | Ecc (n = 104) | P value |
|---|---|---|---|
| Age, median (IQR) | 65 (59, 71) | 57 (51, 68.5) | 0.1 |
| No. by race (%) | |||
| White | 28 (61) | 72 (69) | 0.2 |
| Black | 14 (30) | 30 (29) | |
| Other/unknown | 4 (9) | 2 (2) | |
| No. female gender (%) | 10 (22) | 37 (36) | 0.1 |
| No. with past medical history (%) | |||
| Recent glucocorticoid use | 12 (26) | 19 (18) | 0.3 |
| Neoplasm | 18 (39) | 42 (40) | 1.0 |
| Diabetes mellitus | 15 (33) | 38 (37) | 0.7 |
| Transplant | 5 (11) | 12 (12) | 1.0 |
| Surgery in past 30 days | 14 (30) | 44 (42) | 0.2 |
| Hemodialysis dependence | 4 (9) | 24 (23) | 0.04 |
| Rheumatologic disorder | 1 (2) | 3 (3) | 1.0 |
| No. by site of acquisition (%) | |||
| Community-acquired | 21 (46) | 57 (55) | 0.4 |
| Hospital-acquired | 25 (54) | 47 (45) | |
| No. by source of infection (%) | |||
| Urine/pyelonephritis | 7 (15) | 16 (16) | 0.1 |
| Pneumonia | 4 (9) | 4 (4) | |
| Abscess | 5 (11) | 7 (7) | |
| Line-associated | 5 (11) | 28 (27) | |
| Skin/soft tissue | 0 (0) | 7 (7) | |
| Biliary tract | 5 (11) | 6 (6) | |
| Other | 6 (13) | 8 (8) | |
| Source not identified | 14 (30) | 28 (27) | |
| Mean days to appropriate antibiotic therapy (SD) | 0.8 (1.2) | 0.7 (1.0) | 0.4 |
| No. with appropriate antibiotics on day 0 (%) | 26 (57) | 62 (60) | 0.2 |
| No. with appropriate antibiotics after day 0 (%) | 19 (41) | 41 (39) | |
| APACHE-II acute physiology score, mean (SD) | 8.6 (6.5) | 7.1 (4.4) | 0.1 |
| APACHE-II chronic illness score, mean (SD) | 3.9 (2.1) | 3.8 (2.1) | 0.8 |
| No. with score of 0 (%) | 10 (22) | 25 (24) | 0.8 |
| No. with score of 5 (%) | 36 (78) | 79 (76) | |
a
SD, standard deviation; IQR, interquartile range; Ecc, Enterobacter cloacae complex.