TABLE 3.
Multivariable logistic regression models for total in-hospital mortality, attributable in-hospital mortality, and poor clinical outcome in patients with K. aerogenes and E. cloacae complex bloodstream infectione Predictors with P < 0.05 are in bold
| Predictor | Total mortality (OR [95% CI]) (P value) | Attributable mortality (OR [95% CI]) (P value) | Poor clinical outcome (OR [95% CI]) (P value) |
|---|---|---|---|
| K. aerogenes | 1.2 [0.4, 3.0] (0.8) | 1.5 [0.4, 5.1] (0.5) | 3.3 [1.4, 8.1] (0.008) |
| Age | [1.0, 1.1] (0.05) | 1.1 [1.0, 1.1] (0.01) | 1.0 [1.0, 1.1] (0.04) |
| Racea | 0.7 [0.2, 1.8] (0.4) | 0.3 [0.1, 1.2] (0.09) | 0.7 [0.3, 1.6] (0.4) |
| Female gender | 1.4 [0.5, 4.4] (0.5) | 2.0 [0.5, 9.0] (0.3) | 0.8 [0.3, 1.9] (0.6) |
| Hospital-acquired | 1.1 [0.4, 3.0] (0.9) | 2.6 [0.7, 9.8] (0.2) | 1.8 [0.8, 4.3] (0.2) |
| Infection sourceb | |||
| Pneumonia | 2.5 [0.2, 26.8] (0.4) | 5.2 [0.2, 124.1] (0.3) | 0.4 [0.05, 3.2] (0.4) |
| Abscessc | 0.8 [0.1, 9.9] (0.8) | 0.2 [0.03, 1.0] (0.05) | |
| Line | 0.6 [0.1, 4.1] (0.6) | 2.5 [0.2, 36.5] (0.5) | 0.1 [0.03, 0.4] (0.002) |
| Skind | 0.6 [0.1, 3.9] (0.6) | ||
| Biliary | 1.7 [0.2, 13.5] (0.6) | 7.3 [0.4, 119.5] (0.2) | 0.4 [0.1, 1.9] (0.2) |
| Other | 8.9 [1.4, 57.3] (0.02) | 30.4 [2.0, 471.4] (0.02) | 0.9 [0.2, 4.6] (0.9) |
| Unknown | 6.4 [1.4, 29.8] (0.02) | 8.1 [0.8, 88.4] (0.08) | 0.6 [0.2, 2.0] (0.4) |
| Antibiotics after day 0 | 1.2 [0.4, 3.1] (0.7) | 0.6 [0.2, 2.2] (0.5) | 0.7 [0.3, 1.6] (0.4) |
| Chronic APACHE-II of 5 | 3.1 [1.0, 9.8] (0.06) | 4.3 [0.9, 22.0] (0.08) | 1.6 [0.01, 1.8] (0.1) |
a
Race analyzed as binary (white versus nonwhite).
b
Reference is patients with genitourinary source of infection.
c
Abscess source not included in attributable mortality model due to the small number of cases and events.
d
Skin source not included in total mortality and attributable mortality models due to the small number of cases and events.
e
Predictors with P < 0.05 are in bold; OR, odds ratio; CI, confidence interval.