Table 3.

Propensity Score-Weighted Cox Regression of Factors Associated With Increased Risk of Mortality in pN1 Patients

	Propensity Score-Weighted Cox Regression
Covariate	Hazard Ratio	95% CI	P Value
Treatment
Multiagent adjuvant chemotherapy	Reference
Surgery only	2.11	2.02–2.19	<.001
Sex
Male	1.28	1.23–1.33	<.001
Female	Reference
Age, y
≤69	Reference
>69	1.30	1.25–1.35	<.001
Race/ethnicity
White	Reference
Asian	0.87	0.73–1.03	.096
Black	0.96	0.89–1.03	.235
Hispanic	0.97	0.84–1.12	.670
Other	0.89	0.71–1.11	.299
Education
<20.9% no HS diploma	Reference
>21% no HS diploma	1.02	0.96–1.09	.485
Charlson-Deyo score
0	Reference
1	1.14	1.10–1.19	<.001
2+	1.40	1.32–1.49	<.001
Clinical T stage
1	Reference
2	0.94	0.88–0.99	.047
3	1.06	0.97–1.17	.212
4	1.12	0.98–1.28	.086
Clinical N
0	Reference
1	1.07	1.03–1.11	.001
Pathologic T stage
1	Reference
2	1.11	1.04–1.19	.001
3	1.52	1.39–1.67	<.001
4	1.54	1.38–1.73	<.001
Median household income
<$38,000	1.06	1.01–1.12	.044
≥$38,000	Reference
Urban vs rural status
Urban	Reference
Rural	1.03	0.97–1.09	.282
Insurance status
Not insured or Medicaid	1.22	1.13–1.31	<.001
Other	Reference
Facility type
Academic/research	Reference
Community/integrated cancer	1.11	1.07–1.16	<.001
Tumor grade
Well differentiated	Reference
Moderately differentiated	1.18	1.07–1.30	.001
Poorly differentiated	1.24	1.13–1.37	<.001
Other	1.24	1.09–1.41	.001
Histology
Adenocarcinoma	Reference
Squamous cell carcinoma	0.93	0.89–0.98	.002
Other	0.99	0.91–1.08	.835
Time between diagnosis and surgery
≤90 days	Reference
>90 days	1.08	1.01–1.17	.047
Tumor size
<4 cm	Reference
≥4 cm	1.13	1.22–1.35	<.001
Resection type
Bilobectomy/lobectomy	Reference
Pneumonectomy	1.12	1.06–1.18	<.001
Year of diagnosis
2006	Reference
2007	0.97	0.88–1.07	.557
2008	0.96	0.88–1.04	.317
2009	0.87	0.80–0.95	.002
2010	0.92	0.85–1.01	.067
2011	0.85	0.78–0.93	<.001
2012	0.98	0.90–1.07	.702
2013	0.92	0.84–1.01	.095
2014	...	...	...

Boldface indicates statistical significance (P < .05).

CI, confidence interval; HS, high school.