Table 1.
Plasma application, type of study and plasma sources of research papers discussed in the review.
| PLASMA APPLICATION | TYPE OF STUDY | PLASMA SOURCE | REFERENCES | |||
|---|---|---|---|---|---|---|
|
ORAL BIOFILM | ||||||
| C. albicans + Staphylococcus aureus | In vitro | Argon-based plasma jet (kINPen®09, neoplas tools GmbH, Germany) | [12] | |||
| Enterococcus faecalis | In vitro | Argon-based plasma jet (kINPen®MED, neoplas tools GmbH, Germany) | [36,37] | |||
| Peri-implantitis microcosm biofilm | In vitro | Argon +1% Oxygen based plasma jet (kINPen®08, INP, Germany | [45] | |||
| Streptococcus mitis | In vitro | Argon-based plasma jet (kINPen®MED, neoplas tools GmbH, Germany) | [46] | |||
|
Porphyromonas gingivalis |
In vitro |
Argon-based plasma jet (kINPen®09, neoplas tools GmbH, Germany) |
[13] |
|||
|
WOUND AND SKIN DISEASES | ||||||
| Porphyromonas aeruginosa | In vitro | Argon based or Argon +1% Oxygen based plasma jet (kINPen®09, neoplas tools, GmbH, Germany | [50] | |||
| Staphylococcus epidermidis | In vitro | |||||
| Chronically infected wounds | In vivo (clinical) | Argon-based microwave-driven plasma device (MicroPlaSter alpha and beta, ADTEC Plasma Technology Co. Ltd, Japan/UK) | [51] | |||
| Trichophyton rubrum, Trichophyton interdigitale, Microsporon canis, C. albicans | In vitro | Argon-based plasma jet (kINPen®09, neoplas tools GmbH, Germany) and Dielectric Barrier Discharge (DBD) plasma device | [49] | |||
| Severely contaminated wounds | In vivo (clinical) | Argon-based Maxium® electrosurgery unit with maxium® beamer and beam electrode (Gebrüder Martin GmbH + Co. KG) | [19] | |||
| Non-infected wounds | In vivo (clinical) | Argon-based plasma jet (kINPen®MED, neoplas tools GmbH, Germany) | [52] | |||
| Patients with wound healing disorder | In vivo (clinical) | Argon-based plasma jet (kINPen®MED, neoplas tools GmbH, Germany) | [53] | |||
| Mammalian cell lines related to wound healing | In vitro | Argon-based plasma jet (APPJ device) | [20] | |||
| Diabetic wounds |
In vivo (mice model) |
Helium-based plasma jet and plasma-activated medium (PAM) |
[21] |
|||
|
CANCER THERAPY (DIRECT TREATMENT) | ||||||
| Lung cancer cell lines | In vitro/in vivo (mice model) | Helium-based plasma jet (lab developed at George Washington University) | [54] | |||
| Murine melanoma cell lines (B16–F10) | ||||||
| Bladder cancer tumor cells (SCaBER) | ||||||
| Glioblastoma U87MG | In vitro/in vivo (mice model) | Floating Electrode (FE) – DBD plasma device | [55] | |||
| Colorectal carcinoma HCT-116 | In vitro | |||||
| Murine neuroblastoma | In vitro/in vivo (mice model) | Helium-based plasma jet | [56] | |||
| Breast cancer tumor cell lines (4T1) | In vitro/in vivo (mice model) | Helium-based Micro (μ) Plasma Jet | [57] | |||
| Head and neck cancer cell lines | In vitro | Surface Micro Discharging (SMD) plasma device (MiniFlatPlaSter®) | [22] | |||
| Head and neck squamous cancer |
In vivo (clinical) |
Argon-based plasma jet (kINPen®MED, neoplas tools GmbH, Germany) |
[23] |
|||
|
CANCER THERAPY (INDIRECT TREATMENT) | ||||||
| Immune modulators, Intracellular ROS production inducers |
In vitro/in vivo |
Nanosecond pulsed dielectric barrier discharge (nsDBD) plasma Nonequilibrium atmospheric pressure Plasma (NEAPP) |
[[63], [64], [65], [66]] [[68], [69], [70]] |
|||
|
VIRUSES | ||||||
| Influenza A and B | In vitro | Nitrogen-based plasma device (BLP-TES, NGK Insulators Ltd., Nagoya, Japan) | [75] | |||
| Respiratory syncytial virus (RSV) | In vitro | |||||
| Human adenovirus (HAdV-4, -5, -20, -35, -37, -50) | In vitro | Argon-based plasma jet (kINPen®MED, neoplas tools GmbH, Germany) | [77] | |||
| Herpes simplex virus type 1 (HSV-1) | In vitro | Argon-based plasma jet (kINPen®MED, neoplas tools GmbH, Germany) | [25] | |||
| Herpes zoster |
In vivo (clinical) |
Argon-based microwave-driven plasma device (MicroPlaSter alpha and beta, ADTEC Plasma Technology Co. Ltd, Japan/UK) |
[79] |
|||
|
IMPLANT SURFACES | ||||||
| Surface modification and osseointegration | In vivo (canine model) | Argon-based plasma jet (kINPen®09, neoplas tools GmbH, Germany) | [26] | |||
| Wound healing and osseointegration | In vivo (canine model) | Argon-based plasma jet (kINPen | [82] | |||