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. 2020 Aug 25;3(8):e2012476. doi: 10.1001/jamanetworkopen.2020.12476

Figure 2. One-way Sensitivity Analysis Based on the DAWN Inputs.

Figure 2.

Deterministic 1-way sensitivity analysis of model input parameters grouped by categories based on the DAWN inputs. The plot shows how varying input parameters to the limits reported, 1 at a time, affects the incremental cost-effectiveness ratio (ICER), while keeping all the other model input parameters at their base-case value. The orange bars represent how the lower bounds affect the ICER, and the blue bars represent how the upper bounds affect the ICER. The lengths of the bars reveals the degree of influence that 1 input parameter has on the ICER compared with the base-case ICER of $662 per quality-adjusted life-years. Low and high efficacy of mechanical thrombectomy with standard medical care (MT+SMC) was defined by the following distribution of patients on the modified Rankin Scale (mRS) at 3 months: low efficacy, mRS 0, 7%; mRS 1, 20%; mRS 2, 15%; mrS 3, 14%; mRS 4, 14.5%; mRS 5, 11.5%; and mRS 6, 18%; high efficacy, mRS 0, 10%; mRS 1, 23%; mRS 2, 18%; mRS 3, 13%; mRS 4, 12%; mRS 5, 9%; and mRS 6, 15%. CT indicates computed tomography; CTA, CT angiography; IV-tPA, intravenous tissue plasminogen activator; MRA, magnetic resonance angiography; and MRI, MR imaging.