Table 3.

Tissue concentrations of enrofloxacin (µg/gm) in chickens after multiple oral doses of 10 mg/kg b.wt. once daily for 5 consecutive days

	Organs
Time of slaughter	Chicken groups	Serum	Liver	Kidney	Lung	Brain	Breast muscle	Thigh muscles	Spleen	Heart
2 h	Healthy	2.2	2.7	1.95	1.54	0.8	0.68	0.38	1.53	0.76
	Eimeria infected non-treated	2.46	2.48	1.82	2.07	0.5	2.12	1.45	1.35	0.8
	Eimeria infected treated (Amprolium)	2.16	5.25	3.3	3.1	1.85	2.2	2.07	3.63	2.4
	Eimeria infected treated (Toltrazuril)	0.22	1.79	1.7	1.36	0.47	1.6	1.53	1.2	1.59
1 day	Healthy	0.35	1.09	1.29	0.76	0.4	0.24	0.19	0.76	0.33
	Eimeria infected non-treated	0.36	1.12	0.37	0.32	0.04	0.35	0.4	0.39	0.4
	Eimeria infected treated (Amprolium)	0.7	0.68	0.63	0.3	0.11	0.62	0.48	0.54	0.17
	Eimeria infected treated (Toltrazuril)	0.03	0.03	0.02	0.015	0.004	0.072	0.21	0.007	0.023
3 day	Healthy	0.09	0.53	0.17	0.09	0.03	0.07	0.04	0.19	0.056
	Eimeria infected non-treated	0.03	0.055	0.017	0.025	0.015	0.125	0.35	0.04	0.05
	Eimeria infected treated (Amprolium)	0.03	0.15	0.015	0.051	0.009	0.12	0.11	0.11	0.016
	Eimeria infected treated (Toltrazuril)	–	0.015	0.009	0.009	0.003	0.029	0.014	0.005	0.0075
5 day	Healthy	–	0.3	–	0.004	–	0.019	0.029	–	–
	Eimeria infected non-treated	0.012	0.027	0.005	0.038	0.0085	0.01	0.008	0.011	0.008
	Eimeria infected treated (Amprolium)	0.017	0.06	0.015	0.012	–	0.006	0.006	0.0019	0.005
	Eimeria infected treated (Toltrazuril)	–	0.0075	–	0.02	–	–	–	0.003	0.0035
7 day	Healthy	–	–	–	–	–	–	–	–	–
	Eimeria infected non-treated	0.005	0.0045	0.003	–	–	0.005	0.003	0.0035	–
	Eimeria infected treated (Amprolium)	0.007	0.027	0.007	0.0045	–	0.003	0.002	0.008	–
	Eimeria infected treated (Toltrazuril)	–	–	–	–	–	–	–	–	–
10 day	Healthy	–	–	–	–	–	–	–	–	– -
	Eimeria infected non-treated	–	–	–	–	–	–	–	–	–
	Eimeria infected treated (Amprolium)	–	0.005	0.003	–	–	–	–	0.002	–
	Eimeria infected treated (Toltrazuril)	–	–	–	–	–	–	–	–	–

Not detectable (–).

Mean ± SE (n = 3).