Table 2.
Multivariate linear regression analysis of the association between anthropometrics (predictor) and ovarian reserve indices (outcome)
| AMHa | AFCa | AMH/AFCa | ||||
|---|---|---|---|---|---|---|
| Coeff (95% CI) | P | Coeff (95% CI) | P | Coeff (95% CI) | P | |
| PCOS | ||||||
| BMI (kg/m2) | –0.023 (–0.030, -0.016) | <0.001 | –0.008 (–0.012, 0.003) | 0.001 | –0.015 (–0.021, –0.009) | <0.001 |
| Waist circumference (cm) | –0.010 (–0.013, –0.006) | <0.001 | –0.003 (–0.005, 0.001) | 0.005 | –0.006 (–0.009, –0.004) | <0.001 |
| BSA (m2) | –0.729 (–0.978, –0.481) | <0.001 | –0.231 (–0.394, –0.068) | 0.006 | –0.479 (–0.679, –0.279) | <0.001 |
| OVA | ||||||
| BMI (kg/m2) | –0.019 (–0.027, –0.010) | <0.001 | 0.002 (–0.005, 0.008) | 0.63 | –0.019 (-0.026, –0.013) | <0.001 |
| Waist circumference (cm) | –0.008 (–0.012, –0.004) | <0.001 | 0.000 (–0.003, 0.003) | 0.82 | –0.008 (–0.011, –0.005) | <0.001 |
| BSA (m2) | –0.492 (–0.756, –0.224) | <0.001 | 0.141 (–0.052, 0.333) | 0.15 | –0.603, (–0.795, –0.411) | <0.001 |
Controlled for age, race, smoking, and study center.
Predictors across rows represent separate models for each of the 3 outcomes listed in columns.
Abbreviations: AFC, antral follicle count; AMH, antimüllerian hormone; BMI, body mass index; BSA, body surface area; CI, confidence interval; coeff, coefficient OVA, ovarian aging control cohort; PCOS, polycystic ovary syndrome.
a AMH, AFC, and AMH/AFC outcomes transformed by natural logarithm.