Table 3:

Cerebral microdialysis data

Cerebral microdialysis	DHCA (n = 10)	DHCP (n = 10)	Control (n =4)	P-value DHCA vs DHCP
Initiation LPR, mean ± SEM	14.4 ± 2.96	13.8 ± 5.43	12.6 ± 1.34	0.99
Cooling LPR, mean ± SEM	34.51 ± 14.4	12.4 ± 5.87	11.57 ± 0.57	0.67
Deep hypothermia LPR, mean ± SEM	71.81 ± 4.50	23.89 ± 6.53	16.39 ± 3.39	0.029
Rewarming LPR, mean ± SEM	132.60 ± 13.1	35.56 ± 3.87	17.83 ± 14.4	0.0001
End CPB LPR, mean ± SEM	60.83 ± 3.70	30.04 ± 6.40	16.41 ± 1.55	0.001
Initiation glucose (mg/dl), mean ± SEM	24.55 ± 7.73	23.81 ± 3.65	22.1 ± 4.02	0.99
Cooling glucose (mg/dl), mean ± SEM	15.15 ± 6.74	13.0 ± 3.93	16.41 ± 6.91	0.99
Deep hypothermia glucose (mg/dl), mean ± SEM	10.3 ± 3.71	13.62 ± 3.91	21.37 ± 6.04	0.99
Rewarming glucose (mg/dl), mean ± SEM	5.23 ± 2.15	4.37 ± 1.01	17.44 ± 6.40	0.99
End CPB glucose (mg/dl), mean ± SEM	13.33 ± 6.08	13.52 ± 1.65	14.76 ± 2.87	0.99
Initiation glycerol (μM), mean ± SEM	34.27 ± 5.19	26.4 ± 3.56	22.51 ± 3.32	0.99
Cooling glycerol (μM), mean ± SEM	39.34 ± 6.06	22.3 ± 1.90	23.39 ± 2.72	0.18
Deep hypothermia glycerol (μM), mean ± SEM	34.65 ± 7.38	19.6 ± 4.07	29.59 ± 2.98	0.32
Rewarming glycerol (μM)	49.6 ± 6.44	19.49 ± 6.11	31.75 ± 7.12	0.0016
End CPB glycerol (μM), mean ± SEM	75.3 ± 7.46	38.98 ± 6.12	22.66 ± 1.53	0.0001

Summary of cerebral microdialysis values during each phase of CPB.

CPB: cardiopulmonary bypass; DHCA: deep hypothermic circulatory arrest; DHCP: deep hypothermic continuous perfusion; LPR: lactate/pyruvate ratio; SEM: standard error of the mean.