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. 2020 Jun 2;9(1):1160–1169. doi: 10.1080/22221751.2020.1771218

Figure 4.

Figure 4.

Histological findings from neutropenic mice intravenously challenged with Candida auris. Normal (A) and damaged heart (B) with Mallory’s PTAH staining. PTAH staining performed on the heart of a moribund dissected mouse on day 5 infected with isolate 196 (B) revealed contraction band necrosis or myofibrillar degeneration (yellow arrows). Morphology of C. auris with Periodic Acid Schiff (PAS) staining in the heart’s arterioles on day 1 post infection (C), and in the spleen (D). PAS staining showed blastoconidia and budding yeast cells but never pseudohyphae and hyphae (C–D). Magnification, A-B × 400, C × 1000, D × 400, RBC; red blood cells.