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The BBB is comprised of tightly packed endothelial cells that act as a barrier preventing foreign substances from entering the brain. Essential nutrients can pass through the BBB via passive transport, passage through specific proteins or channels, receptor mediated transport, and adsorptive transcytosis. Adapted from Nanotechnology-based Targeted Drug Delivery Systems for Brain Tumors https://doi.org/10.1016/B978-0-12-812218-1.00003-8.
