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. Author manuscript; available in PMC: 2021 Sep 1.
Published in final edited form as: Peptides. 2020 Jul 13;131:170369. doi: 10.1016/j.peptides.2020.170369

Figure 20. A Novel Dermorphin/Deltorphin Inspired Glycopeptide with Reduced Side Effects.

Figure 20.

BBI-11008 is a δ-selective agonist with antinociceptive effects in models of acute and chronic pain and shows an improved side effect profile compared to morphine and fentanyl. BBI-11008 was also able to induce antinociception in a model of acute thermal pain following oral administration. (Bilsky and Polt 2020) [95]