Table 3.
Comparison of patients with and without pneumonitis.
| Variable | Pneumonitis group (n = 43) |
No pneumonitis group (n = 50) | p value |
|---|---|---|---|
| Age [mean (SD)] | 36.3 (11.1) | 29.5 (8.2) | 0.001 |
| Female (n, %) | 19 (44) | 34 (68) | 0.02 |
| Vaccination status (n, %) | <0.001 | ||
| None | 6 (14) | 6 (12) | |
| Incomplete | 20 (46.5) | 5 (10) | |
| Unknown | 17 (39.5) | 39 (78) | |
| Antibiotic use (n, %) | 31 (72) | 24 (49) | 0.02 |
| Symptoms duration before admission in days [median (IQR)] | 4 (3−5) | 4 (3−5) | 0.54 |
| Hospitalization duration in days [median (IQR)] | 6 (3) | 5 (3) | 0.37 |
| Conjunctivitis (n, %) | 16 (37) | 11 (22) | 0.10 |
| Lymphadenopathy (n, %) | 4 (10) | 10 (21) | 0.15 |
| Nasal discharge (n, %) | 10 (23) | 6 (12) | 0.15 |
| Rash (n, %) | 42 (98) | 47 (94) | 0.38 |
| Koplik spots (n, %) | 13 (32) | 17 (36) | 0.66 |
| Pharyngitis (n, %) | 12 (28) | 16 (32) | 0.67 |
| GI symptoms | 13 (30) | 16 (33) | 0.75 |
| WBC count (x109/L [mean (SD)] | 4.7 (1.9) | 4.9 (2.5) | 0.72 |
| Lymphocyte count nadir (x106/L) [mean (SD)] | 420 (220) | 610 (400) | 0.005 |
| Lymphocyte count on admission (x106/L) [mean (SD)] | 490 (290) | 740 (510) | 0.006 |
| Neutrophil count on admission (x109/L) [mean (SD)] | 4.1 (1.7) | 3.9 (2.4) | 0.68 |
| Monocyte count on admission (x106/L) [mean (SD)] | 441 (280) | 400 (254) | 0.46 |
| CRP (mg/L) [mean (SD)] | 40.5 (25.0) | 54.6 (38.7) | 0.04 |
| ALT, U/L [mean (SD)] | 149 (146) | 148 (124) | 0.97 |
ALT: alanine aminotransferase, CRP: C-reactive protein, GI: gastrointestinal, IQR: interquartile range, L: liter, n: number of patients, SD: standard deviation, U: units, WBC: white blood cell count.