Table 5.
. Characteristics and outcomes of ribarivin group in patients with pneumonitis and hepatic involvement.
|
Pneumonitis |
Hepatic involvement |
|||||
|---|---|---|---|---|---|---|
| Variable | Ribavirin (+) (n = 8) | Ribavirin (-) (n = 35) | p value | Ribavirin (+) (n = 6) | Ribavirin (-) (n = 69) | p value |
| Lymphocyte count nadir (x106/L) [mean (SD)] | 541 (186) | 389 (221) | 0.08 | 546 (197) | 505 (327) | 0.76 |
| Lymphocyte count on admission (x106/L) [mean (SD)] | 718 (389) | 447 (241) | 0.15 | 781 (429) | 583 (381) | 0.23 |
| PaO2/FiO2 ratio* [mean (SD)] | 254 (63) | 297 (65) | 0.17 | 262 (65) | 379 (70) | 0.001 |
| Hospitalization duration in days [median (IQR)] | 7.5 (6−9) | 6 (4−7) | 0.28 | 7.5 (5.75−9) | 6 (5−7) | 0.24 |
| Age [mean (SD)] | 38 (16.2) | 35.9 (9.8) | 0.65 | 36 (18.4) | 32 (9.4) | 0.48 |
| Female, n (%) | 4 (50) | 15 (43) | 0.71 | 3 (50) | 39 (56.5) | 0.76 |
| ALT (U/L) [mean (SD)] | 141 (188) | 151 (138) | 0.86 | 179 (206) | 179 (126) | 0.99 |
*Data from 21 patients (pneumonitis comparison) and 46 patients (hepatic involvement comparison).
ALT: alanine aminotransferase, FiO2: fraction of inspired oxygen, IQR: interquartile range, L: liter, n: number of patients, PaO2: arterial partial pressure of oxygen, SD: standard deviation, U: units.