Table 1.

Phenotypic characteristics of 118 fetuses with CFMs

Abnormalities	Isolated CFM (N)	Non-isolated CFM (N)	Referred cases (N)
Cranial malformations			41 (34.7%)
Microcephaly	5	4	9
Macrocephaly	1	5	6
Defect in the skull bone	0	13	13
Abnormal skull shape	3	10	13
Orofacial clefts			44 (37.3%)
cleft lip	6	4	10
cleft palate	0	1	1
cleft lip and palate	19	14	33
Ocular and orbital malformations			6 (5.1%)
Hypertelorism	0	3	3
Hypotelorism	0	2	2
Microphthalmia, Cataract	0	1	1
Nasal deformity	5	0	5 (4.2%)
Ear abnormality	2	1	3 (2.5%)
Macroglossia	0	1	1 (0.8%)
Micrognathia	1	0	1(0.8%)
Complex CFMs	5	12	17 (14.4%)
Total	47 (39.8%)	71 (60.2%)	118 (100%)

CFM craniofacial malformation