Skip to main content
. 2020 Aug 25;13:38. doi: 10.1186/s13039-020-00502-5

Table 4.

Detection rate of clinically significant chromosomal aberrations in fetuses with various CFMs

Malformation Simple CFMs Complex CFMs (n/N) Referred cases (n/N, %)
Cranial malformation (n/N) Orofacial cleft (n/N) Nasal deformity (n/N) Ocular malformation (n/N) Ear abnormality (n/N) Macroglossia (n/N) Micrognathia (n/N)
Isolated CFMs 1/9 5/25 0/5 0/0 0/2 0/0 1/1 0/5 7/47, 14.9%
Non-isolated CFMs 10/32 8/19 0/0 1/6 1/1 0/1 0/0 6/12 26/71, 36.6%
Total 11/41 13/44 0/5 1/6 1/3 0/1 1/1 6/17 33/118, 28.0%

CFM craniofacial malformation