Table 2.
Comparison of baseline mean for BMI and serum nesfatin-1, glucose indices, and lipid profile in overweight or obese patients with type 2 diabetes mellitus (T2DM)
| Baseline Dependent Variables | Caraway (n = 27) n(%) or Mean (SD) |
Placebo (n = 25) n(%) or Mean (SD) |
P-value* |
|---|---|---|---|
| BMI (kg/m2) | 28.77(3.77) | 29.19(3.27) | 0.69 |
| WC (cm) | 100.32(7.06) | 100.35(8.45) | 0.94 |
| FBG (mg/dl) | 175.38(69.89) | 174.04(52.30) | 0.92 |
| FBI (μIU/ml) | 9.39(6.77) | 11.63(7.51) | 0.31 |
| HOMA-IR (score) | 4.21(3.72) | 4.98(3.11) | 0.47 |
| QUICKI (score) | 0.45(0.01) | 0.44(0.01) | 0.57 |
| Nesfatin-1 (ng/ml) | 4.37(1.65) | 5.46(2.14) | 0.07 |
| TC (mg/dl) | 159.04(36.78) | 152.62(48.96) | 0.61 |
| TG (mg/dl) | 163.34(117.15) | 164.23(82.37) | 0.97 |
| LDL-C (mg/dl) | 81.34(27.61) | 83.27(29.58) | 0.82 |
| HDL-C (mg/dl) | 44.96(11.99) | 42.95(7.65) | 0.51 |
*t-test; BMI: body mass index, WC: waist circumference, HOMA-IR: homeostasis model assessment-insulin resistance, QUICKI: quantitative insulin sensitivity check index, FBG: fasting blood glucose, FBI: fasting blood insulin, TC: total cholesterol, TG: triglyceride, HDL-C: high-density lipoprotein cholesterol, LDL-C: low-density lipoprotein-cholesterol