Table 1.
Subject’s characteristics in Euthyroid group and Euthyroid women with TPOAb positivity group
| Euthyroid group (n = 837) | Euthyroid women with TPOAb positivity group (n = 101) | Statistics | P | |
|---|---|---|---|---|
| Maternal age (years) | 30 (28,34) | 31 (29,34) | −1.660 | 0.097 |
| Age ≥ 35 years (%) | 157 (18.8%) | 21 (20.8%) | 0.243 | 0.622 |
| BMI (kg/m2) | 21.48 (19.81,23.43) | 21.35 (20.07,23.19) | −0.149 | 0.881 |
| BMI ≥ 24 kg/m2 (%) | 174 (20.8%) | 19 (18.8%) | 0.215 | 0.643 |
| Parity (%) | ||||
| primipara | 519 (62.0%) | 60 (59.4%) | 0.258 | 0.611 |
| multipara | 318 (38.0%) | 41 (40.6%) | ||
| History of spontaneous abortion (%) | 114 (13.6%) | 11 (10.9%) | 0.581 | 0.446 |
| HbA1c (%) | 5.1 (4.9,5.3) | 5.1 (5.0,5.3) | −1.174 | 0.240 |
| GS (mmol/L) | 4.88 (4.65,5.14) | 4.85 (4.65,5.15) | −0.175 | 0.861 |
| TSH (uIU/ml) | 1.31 (0.826,1.80) | 1.51 (1.14,2.08) | −3.793 | 0.000* |
| FT4 (pmol/L) | 17.20 (15.80,18.50) | 16.9 (15.80,18.80) | −0.318 | 0.751 |
| LDL (mmol/L) | 2.02 (1.69,2.37) | 1.98 (1.77,2.28) | −0.426 | 0.670 |
| UA (μmol/L) | 209 (181,236) | 215 (189,239) | −0.841 | 0.401 |
| Hcy (μmol/L) | 6.40 (5.70,7.20) | 6.1 (5.70,7.38) | −0.224 | 0.823 |
| Ferritin (ng/ml) | 53.1 (33.03,80.95) | 48.75 (29.95,69.30) | −1.426 | 0.154 |
*P < 0.05
Statistics: Maternal age, BMI, FT4, TSH, GS, HbA1c, LDL, UA, Hcy and Ferritin for Mann-Whitney U test; Age<35 years, BMI<24 kg/m2, parity, and history of spontaneous abortion for chi-square test or Fisher test
Continuous data are expressed as median (interquartile range). Categorical data are expressed as numbers (percentages) of cases
BMI body-mass index, TSH thyroid-stimulating hormone, FT4 free thyroxine, HbA1c glycated hemoglobin, GS blood glucose, LDL low density lipoprotein cholesterol, UA uric acid, Hcy homocysteine