Table 4.

Logistic regression analysis with euthyroid women with TPOAb positivity as independent variables and poor pregnancy and fetal outcomes as categorical dependent variables

GDM	Total		Pregnant women with a female fetus		Pregnant women with a male fetus
	OR (95% CI)	P	OR (95% CI)	P	OR (95% CI)	p
Model 1	0.991 (0.558–1.760)	0.975	0.596 (0.239–1.483)	0.239	1.696 (0.801–3.591)	0.168
Model 2	1.282 (0.610–2.694)	0.512	0.690 (0.215–2.218)	0.534	2.349 (0.831–6.638)	0.107
Spontaneous abortion
Model 1	1.925 (0.709–5.222)	0.199
Model 2	1.083 (0.227–5.171)	0.920
PROM
Model 1	0.757 (0.399–1.436)	0.383	0.641 (0.239–1.717)	0.197	0.914 (0.386–2.168)	0.914
Model 2	0.476 (0.181–1.250)	0.132	0.835 (0.264–2.640)	0.758	0.391 (0.084–1.831)	0.233
Preterm Birth
Model 1	1.765 (0.713–4.370)	0.219	3.650 (1.195–11.154)	0.023*	1.487 (0.415–5.328)	0.543
Model 2	2.202 (0.699–6.937)	0.178	4.511 (1.075–18.926)	0.04*	0.856 (0.103–7.116)	0.886
Fetal distress
Model 1	1.680 (0.755–3.736)	0.204	2.669 (0.999–7.129)	0.05	0.826 (0.183–3.734)	0.804
Model 2	1.084 (0.307–3.820)	0.900	1.902 (0.371–9.472)	0.440	0.769 (0.091–6.487)	0.809
Low Birth weight
Model 1	1.233 (0.480–3.171)	0.663	1.117 (0.246–5.074)	0.886	1.887 (0.394–9.023)	0.427
Model 2	1.128 (0.251–5.073)	0.875	0.617 (0.072–5.314)	0.661	2.467 (0.486–12.532)	0.276
Fetal macrosomia
Model 1	0.413 (0.098,1.745)	0.229	0.54 (0.069–4.218)	0.557	0.385 (0.050–2.944)	0.358
Model 2	0.401 (0.094–1.707)	0.216	0.504 (0.63–4.030)	0.518	0.375 (0.049–2.893)	0.347

*P < 0.05

Model 1: Adjusted for age, BMI, parity, and history of spontaneous abortion

Model 2: Additionally, adjusted for HbA1c and TSH

BMI body-mass index, TSH thyroid-stimulating hormone, HbA1c glycated hemoglobin, GDM gestational diabetes, PROM premature rupture of membranes