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. 2020 Aug 26;17:73. doi: 10.1186/s12986-020-00491-7

Table 2.

Summary of Technical Depth of Orbitrap-, QTOF-, and Triple-TOF-based Studies. A protein only needs to be identified in one sample to contribute to the total number of unique proteins (indicated as “total” below), thus the total is typically larger in studies with greater sample numbers. An iTRAQ or TMT set is a pool of samples that are run on the LC-MS/MS concurrently. Because the samples in a set are all analyzed simultaneously, a set's contribution to the total number of unique proteins is similar to that of a single sample

Study Year Platform Tissue # Proteins Identified # Samples
[30] 2018 Orbitrap mouse embryo heads

group 1: 313 total

group 2: 372 total

2 groups
[31] 2018 Triple-TOF gerbil plasma 109 total 30
[32, 185, 187] 2015 Orbitrap human plasma

4,705 total

589/set

72 iTRAQ sets
[42] 2018 QTOF rat thalami 1,440 total 6 x 3 tech. reps.
[51] 2017 QTOF duck livers 1,749 total 3 iTRAQ sets
[52] 2019 QTOF fetal duck livers 3,801 total 1 iTRAQ set
[91] 2019 Triple-TOF rat hippocampi 4,807 total 2 iTRAQ sets
[120] 2015 Orbitrap human follicular fluid 227 total 1 TMT set
[121] 2014 QTOF mouse intestine 2,039 total 10
[156] 2019 Orbitrap pig plasma 534 total 45
[157] 2018 Orbitrap mouse liver fraction 4,058 total 9
[158] 2014 QTOF zebrafish 2,956 total 19
[183] 2016 Orbitrap mouse lung

1,160 total,

240 common to all

34
[184] 2018 Orbitrap mouse brain 5,062 total 1 TMT set
[188] 2016 Orbitrap human serum 1,841 total 1 iTRAQ set
[186] 2019 Orbitrap mouse brain tissues

group 1: 5,847 total

group 2: 6,047 total

2 groups of 6
[206] 2013 QTOF rabbit aortae 100 total 24 x 3 tech. reps.