Table 5.
Mortality due to sepsis and blood culture results
| Exposure | N exposed | Mortality due to sepsis [%] | Odds ratio* (95% CI) | p* |
|---|---|---|---|---|
| Gestational age [OR per additional week] | 12.823 | 2.2 | 0.7 (0.66–0.75) | < 0.001 |
| Discharge 2014–2018 | 8.903 | 2.1 | 0.9 (0.73–1.23) | 0.69 |
| Female sex | 5.950 | 1.8 | 0.7 (0.58–0.95) | 0.02 |
| Multiple birth | 3.979 | 2.0 | 0.9 (0.70–1.22) | 0.59 |
| SGA | 1.753 | 4.1 | 2.0 (1.49–2.58) | < 0.001 |
| All blood cultures negative* | 10.893 | 1.5 | Ref. | |
| Staph. epidermidis | 745 | 2.4 | 1.2 (0.7–2.0) | 0.74 |
| Staph. haemolyticus | 196 | 5.1 | 2.6 (1.3–5.0) | 0.005 |
| E coli | 169 | 11.2 | 7.3 (4.3–12) | < 0.001 |
| Staph. aureus | 150 | 4.0 | 2.3 (1.00–5.3) | 0.053 |
| Staph. capitis | 105 | 0 | – | |
| Enterococci, no VRE | 97 | 8.2 | 4.2 (2.0–9.0) | < 0.001 |
| Enterobacter spp. | 94 | 6.4 | 3.4 (1.4–7.9) | 0.005 |
| Group B Strep. | 86 | 9.3 | 5.5 (2.6–12) | < 0.001 |
| Klebsiella, no MDRO | 75 | 10.7 | 5.6 (2.6–12) | < 0.001 |
| Candida spp | 45 | 26.7 | 16 (7.9–32) | < 0.001 |
| E. coli ESBL | 32 | 12.5 | 6.7 (2.3–20) | 0.001 |
| Staph. hominis | 28 | 7.1 | 4.0 (0.9–17) | 0.06 |
| Enterococci, VRE | 20 | 5.0 | 2.8 (0.4–21) | 0.33 |
| Serratia | 17 | 5.9 | 2.9 (0.4–23) | 0.30 |
| Klebsiella ESBL | 16 | 0 | – | |
| MRSA | 16 | 6.3 | 3.7 (0.5–28) | 0.21 |
| Pseudomonas | 14 | 57.1 | 59 (19–180) | < 0.001 |
| Other streptococci | 12 | 0 | – | |
| Listeria | 8 | 12.5 | 11 (1.3–92) | 0.04 |
| Pneumococci | 3 | 0 | – | |
| Proteus | 1 | 0 | – | |
| Bacteroides | 1 | 0 | – |
*Logistic regression, result of last positive blood culture before death or discharge was entered as category variable with all blood-culture negative infants as reference