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. 2020 Aug 26;22:95. doi: 10.1186/s13058-020-01332-4

Table 1.

Characteristics of the study population (n = 1040) at blood draw and study entry

Characteristic No. Mean (SD) or %
 Age at blood draw, years 1040 57.9 (9.3)
 BMI at study entry, kg/m2 1040 25.3 (4.0)
 Age at menarche, years 1016 13.2 (1.5)
 Ever use of contraceptives, % 1028 83.9
 Number of births, n 1039 1.9 (1.1)
 Age at first birth, years 921 26.8 (5.2)
 Postmenopausal, n 705 67.8
 Age at menopause, years 371 49.6 (5.4)
 Alcohol consumption, g/day 1035 6.9 (8.3)
 Physical activity, MET-h/d 1040 42.4 (6.4)
 Previous use of MHT, % 1040 24.4
 Mammographic features
  Mammographic density, dense area, cm2 1040 24.9 (22.2)
  Mammographic density change, dense area, cm2/year 1040 − 0.8 (3.3)
Circulating hormones Median (SD)
 Progestogens
  Pregnenolone, ng/mL 718 5.3 (10.2)
  Progesterone, ng/mL 905 3.9 (22.4)
  17OH-progesterone, ng/mL 910 2.1 (11.4)
 Androgens
  DHEA, ng/mL 768 22.0 (45.2)
  DHEAS, μg/mL 974 1.8 (2.2)
  Androstenedione, ng/mL 817 4.8 (24.6)
  Testosterone, ng/mL 829 2.0 (11.1)
  Free testosterone, pg/mL 824 46.6 (312.0)
  Androsterone, ng/mL 711 13.1 (17.0)
  Etiocholanolone, ng/mL 654 6.1 (10.4)
 Oestrogens
  Oestrone, ng/mL 450 6.3 (21.5)
  Oestrone sulphate, ng/mL 938 7.1 (21.3)
 Corticoids
  Corticosterone, ng/mL 915 4.1 (14.4)
  Aldosterone, ng/mL 565 0.8 (2.5)
  11-Deoxycortisol, ng/mL 866 3.2 (15.1)
  Cortisol, ng/mL 914 128.8 (61.7)
  Cortisone, ng/mL 909 44.7 (35.1)
 Peptide hormones and proteins
  Prolactin, ng/mL 1035 15.4 (14.2)
  SHBG, μg/mL 1034 4.1 (2.4)

BMI body mass index, DHEA dehydroepiandrosterone, DHEAS dehydroepiandrosterone sulphate, MET metabolic equivalent of task, MHT menopausal hormone therapy, SD standard deviations, SHBG sex hormone-binding globulin