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. 2020 Aug 25;21:740. doi: 10.1186/s13063-020-04635-1

Table 1.

Intermittent feeding protocol (experimental group)

Time 06:00–06:30 10:30 11:00–11:30 15:30 16:00–16:30 20:30 21:00–21:30 01:30
Nutrition Break GRV Nutrition Break GRV Nutrition Break GRV Nutrition Break GRV Break
Day 1
Protein dose1 0.1 0.2 0.4 0.4
Flow rate2 50–90 100–180 200–360 200–360
Total protein3 0.1 0.3 0.7 1.1
Day 2
Protein dose1 0.4 0.4 0.4 0.4
Flow rate2 200–360 200–360 200–360 200–360
Total protein3 1.4 1.6 1.6 1.6

GRV gastric residual volume

1[g/kgBW/30 min], 4 nutrition cycles/24 h: each with 30 min nutrition followed by a 4-h break and 30 min GRV measure, night time break of 4 h. Total time of feeding, 2 h; GRV measurements, 2 h; break, 20 h

2[ml Fresubin© Intensive/30 min], depending on bodyweight

3Total of administered protein of the preceding 24 h [g/kgBW]