Title	Protein delivery in intermittent and continuous enteral nutrition with a protein-rich formula in critically ill patients A protocol for the prospective randomised controlled proof-of-concept Protein Bolus Nutrition (Pro BoNo) study
Trial registration	ClinicalTrials.gov Identifier: NCT03587870, registered July 16, 2018. Swiss National Clinical Trial Portal identifier: SNCTP000003234, last updated July 24, 2019.
Protocol version	Clinical Study Protocol Version 4, 15.07.2019
Funding	Goldschmidt-Jacobson Foundation (approval June 2018): full salary for one doctoral student working full time on this study
Author details	Simona Reinhold1*, Desirée Yeginsoy1*, Alexa Hollinger1, Atanas Todorov1, Lionel Tintignac2, Michael Sinnreich3, Caroline Kiss4, Caroline E. Gebhard1, Balázs Kovács5, Bianca Gysi1, Lara Imwinkelried1, Martin Siegemund1 1Intensive Care Unit, University Hospital Basel, Basel, Switzerland 2Department of Biomedicine, University Hospital Basel, Basel, Switzerland 3Departments of Biomedicine and Neurology, Centre of Neuromuscular Diseases, University Hospital Basel, Basel, Switzerland 4Department of Clinical Nutrition, University Department of Geriatric Medicine Felix Platter, Basel, Switzerland 5Department of Radiology, Musculoskeletal Diagnostics, University Hospital Basel, Basel, Switzerland
Name and contact information for the trial sponsor	Martin Siegemund, MD Deputy Head of Intensive Care Unit University Hospital Basel Tel. +41 61 328 64 14
Role of sponsor	Concept and design of study. Coordination of study together with the Intensive Care Unit research team of the University Hospital Basel. Responsibility for the integrity of the data and the accuracy of the data analysis.