TABLE 2.

In vivo parasitemia inhibition of P. yoelii 17XNL-infected mice treated with epirubicin for 4 days

Group	Mean percentage parasitemia ± SD (% inhibitiona of parasite growth)
	Day 3	Day 5	Day 7
Nontreated	1.3 ± 0.8	1.7 ± 0.4	3.6 ± 1.5
Treated with epirubicin (mg/kg)
2	0.6 ± 0.4 (56)	2.2 ± 1.5 (0)	6.9 ± 5.3 (0)
4	0.2 ± 0.2 (82)	1.4 ± 1.2 (19)	7.5 ± 6.1 (0)
6	0.1 ± 0.1 (95)	0.4 ± 0.3 (78)	1.8 ± 1.3 (51)

^aValues are expressed as mean percentage parasitemia inhibition relative to nontreated control. Data are means ± SD and are derived from three independent experiments (control, n = 18; 2 mg/kg, n = 16; 4 mg/kg, n = 15; 6 mg/kg, n = 16).