. 2020 Aug 20;64(9):e01168-20. doi: 10.1128/AAC.01168-20

TABLE 3.

Univariable and multivariable analyses of factors associated with hospital mortality in patients with SARS-COV-2 infection^a

Variable	Univariable analysis		Multivariable analysis		Multivariable adjusted according to propensity score
Variable	OR (95% CI)	P value	OR (95% CI)	P value	OR (95% CI)	P value
Age	1.12 (1.08–1.15)	*<0.001*	1.13 (1.08–1.18)	*0.048*	1.11 (1.05–1.18)	*<0.001*
Age-adjusted Charlson score	1.34 (1.21–1.49)	*<0.001*
Underlying medical conditions	3.6 (1.5–8.6)	*0.002*
High blood pressure	3.1 (1.8–5.3)	*<0.001*
Ischemic heart disease	3.1 (1.7–5.4)	*<0.001*
Diabetes	2.8 (1.6–4.9)	*<0.001*
Dyslipidemia	2.0 (1.2–3.4)	*0.011*
Cardiovascular risk factors	2.5 (1.4–5.7)	*0.003*
Chronic kidney disease	9.2 (4.1–20.5)	*<0.001*	29.13 (7.93–107.03)	*<0.001*	43.28 (6.90–273.87)	*<0.001*
Onco-hematologic disease	2.5 (1.3–4.6)	*0.005*
Transplant (SOT/SCT)	8.9 (2.5–32.6)	*0.001*
Neurologic disease	3.1 (1.6–6.1)	*0.002*
Hydroxychloroquine	0.13 (0.28–0.59)	*0.013*
Lopinavir-ritonavir	0.42 (0.25–0.70)	*0.001*
PaO₂/FiO₂ (on D0)	0.99 (0.98–0.99)	*<0.001*
SatO₂/FiO₂ (on D0)	0.99 (0.991–0.998)	*<0.001*
ARDS	1.77 (1.01–3.09)	*0.046*	2.00 (1.14–3.51)	*0.015*	1.17 (0.51–2.67)	0.714
Lactate dehydrogenase (on D0)	1.003 (1.001–1.005)	*0.001*	1.004 (1.00–1.01)	*0.002*	1.001 (1.00–1.01)	*0.012*
d-Dimer (on D0)	1.04 (1.00–1.07)	*0.036*
C-reactive protein (on D0)	1.004 (1.001–1.008)	*0.011*
Steroid treatment	0.51 (0.27–0.96)	*0.044*	0.34 (0.12–0.99)	*0.048*	0.19 (0.05–0.74)	*0.016*

SOT, solid organ transplantation; SCT, stem cell transplantation; D0, day 0; PaO₂/FiO₂, arterial oxygen tension/inspiratory oxygen fraction; SatO₂/FiO₂, oxygen saturation/inspiratory oxygen fraction; ARDS, acute respiratory distress syndrome.