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. 2020 Aug 20;64(9):e00152-20. doi: 10.1128/AAC.00152-20

TABLE 3.

Resistance index for the AP-selected lines in the extracellular promastigote assay^a

Compound	Wild type vs LEM3323Cl₄/1044Cl₁			Wild type vs LEM3323Cl₄/8012Cl₂
	Mean IC₅₀ (μM) ± SEM		RI	Mean IC₅₀ (μM) ± SEM		RI
	Wild type	LEM3323Cl₄/1044Cl₁	RI	Wild type	LEM3323Cl₄/8012Cl₂	RI
DNDI-1044	0.50 ± 0.06	2.79 ± 0.61	5.6	0.50 ± 0.06	2.52 ± 0.81	5.0
DNDI-8012	0.67 ± 0.12	3.48 ± 0.75	5.2	0.67 ± 0.12	3.70 ± 1.17	5.5
DNDI-5561	0.82 ± 0.16	4.45 ± 0.93	5.4	0.82 ± 0.16	6.57 ± 0.76	8.0

^a

Results are based on two independent replicates run in duplicate. RI, resistance index.