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. 2020 Aug 20;64(9):e00152-20. doi: 10.1128/AAC.00152-20

TABLE 4.

Resistance index for the AP-selected lines in the intracellular amastigote assay^a

Compound	Wild type vs LEM3323Cl₄/1044Cl₁			Wild type vs LEM3323Cl₄/8012Cl₂
	Mean IC₅₀ (μM) ± SEM		RI	Mean IC₅₀ (μM) ± SEM		RI
	Wild type	LEM3323Cl₄/1044Cl₁	RI	Wild type	LEM3323Cl₄/8012Cl₂	RI
DNDI-1044	0.18 ± 0.05	0.61 ± 0.08	3.4	0.21 ± 0.03	0.20 ± 0.01	1.0
DNDI-8012	0.30 ± 0.09	0.90 ± 0.10	3.0	0.28 ± 0.02	0.42 ± 0.02	1.5
DNDI-5561	0.10 ± 0.003	0.37 ± 0.09	3.6	0.16 ± 0.01	0.28 ± 0.10	1.8

^a

Results are based on two independent replicates run in duplicate. RI, resistance index.