Skip to main content
. 2020 Aug 20;64(9):e00578-20. doi: 10.1128/AAC.00578-20

TABLE 2.

Primary, secondary, and other predefined endpointsa

Endpoint Median (IQR) or no. (%)
P value
Pre-AXDX group (n = 84) Post-AXDX group (n = 89)
Time to first antibiotic intervention (h) 26.3 (4.5–43.6) 8 (6.5–11.3) 0.003
Time to most targeted therapya (h) 14.4 (0–49.6) 9.0 (0–18.5) 0.03
14-day mortality 3 (3.6) 0 0.11
Hospital LOS (days) 8 (6–10.75) 6 (4.5–8.5) 0.002
Hospital LOS post-positive BCb (days) 6 (4–9) 5 (3–7) 0.01
ICU LOS post-positive BC (days) 3 (2–6.25) 2 (2–2.5) 0.25
Antibiotic intensity scorec 16 (10.5–20) 12 (9–15.5) 0.0002
30-day readmission 7 (8.6) 5 (5.6) 0.44
Broad-spectrum antibiotics (days) 3 (2–3) 1 (0.5–2) <0.0001
a

After positive blood cultures.

b

BC, blood cultures.

c

Calculated at 96 h of antibiotic therapy.