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In vitro susceptibility to DAP and host defense peptide (HDP) LL-37 in J01/J03 and J03 passage isolates
| Isolate | Passage | DAP MIC (mg/liter) | % survival (mean + SD) after 2 h of exposure to LL-37 concn of: |
|
|---|---|---|---|---|
| 2 mg/liter | 5 mg/liter | |||
| J01 | 0.5 | 82 ± 9 | 8 ± 1 | |
| J03 | 3 to 4 | 92 ± 21 | 46 ± 8 | |
| J03 | Media | 1 | 95 ± 2 | 61 ± 7a |
| NAF | 1 | 84 ± 8 | 51 ± 9 | |
| LOX | 0.125 | 75 ± 13a | 7 ± 10a | |
| CRO | 2 | 97 ± 1 | 63 ± 4a | |
| FOX | 2 | 98 ± 1 | 68 ± 6a | |
P < 0.05 versus DAP-NS J03.
