TABLE 4.

Probability of target attainment using weight-based dosing regimens of caspofungin

Loading dose	Maintenance dose	PTA (%) by AUC (mg·h/liter)
		0–24 h		48–72 h		120–144 h		192–216 h		264–288 h		312–336 h
		≥98	≥200	≥98	≥200	≥98	≥200	≥98	≥200	≥98	≥200	≥98	≥200
2 mg/kg	1 mg/kg	98	21	91	6	88	5	89	5	89	5	89	5
1.5 mg/kg	1.25 mg/kg	83	3	99	13	100	16	100	17	100	18	100	18
2 mg/kg	1.25 mg/kg	98	21	100	15	100	16	100	17	100	18	100	18
1 mg/kg		22	0	77	2	88	5	89	5	89	5	89	5
1.5 mg/kg		83	3	100	25	100	31	100	33	100	33	100	33