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Probability of target attainment for the first 24 h for 4 g cefepime infused over 4 h, followed by continuous infusion. The target was 100% fT>MIC (A) or 100% fT>4×MIC (B). Horizontal dashed lines indicate a 90% probability of target attainment. The mean (SD) creatinine clearance and weight used for the simulations were 116 (92) ml/min and 86 (34) kg, respectively. CI, continuous infusion.
