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. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: Curr Opin Biomed Eng. 2019 Sep 23;12:51–58. doi: 10.1016/j.cobme.2019.09.007

Figure 1.

Figure 1.

Mathematical analysis of action potential filtering by detectors with different response times. A. Plots of voltage versus time for an action potential simulated by integrating the Hodgkin-Huxley equations (gray trace), and by filtering this waveform according to Eq. 3 with the indicated sensor time constants (tau; black traces). Note the uptick in the Hodgkin-Huxley spike at 1.1 msec reflects the brief 0.1 msec current pulse added mathematically to trigger the spike. B. Plot of amplitude versus tau. C. Plot of width at half maximum (WHM) versus tau.