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. 2020 Aug 22;12(8):e9937. doi: 10.7759/cureus.9937

Table 4. Comparison of Liraglutide with OADs and Insulin.

BMI, body mass index; HbA1C, glycated hemoglobin; OADs, oral anti-diabetics

S. No .Variables Pre-treatment (Mean) Post-treatment (Mean) Difference p-Value
  Group 1: Liraglutide as Monotherapy (n=18)
1 Weight 91.77 85.38 6.39 <0.001
2 BMI 32.85 30.26 2.59 <0.001
3 HbA1C 8.58 6.79 1.79 <0.001
4 Fasting Glucose Levels 189.72 118.22 71.5 <0.001
5 Systolic Blood Pressure 130.83 117.77 13.06 0.001
6 Diastolic Blood Pressure 88.61 81.11 7.50 <0.001
  Group 2: Liraglutide with OADs (n=25)
1 Weight 93.88 89.09 4.79 <0.001
2 BMI 33.36 31.58 1.78 <0.001
3 HbA1C 9.73 7.98 1.75 <0.001
4 Fasting Glucose Levels 202.92 124.40 78.52 <0.001
5 Systolic Blood Pressure 140.56 126.40 14.16 <0.001
6 Diastolic Blood Pressure 89.52 83.84 5.68 0.008
  Group 3: Liraglutide with Insulin (n=27)
1 Weight 95.00 89.60 5.4 <0.001
2 BMI 34.78 32.70 2.08 <0.001
3 HbA1C 10.08 8.32 1.76 <0.001
4 Fasting Glucose Levels 239.25 143.03 96.22 <0.001
5 Systolic Blood Pressure 137.22 126.29 10.93 <0.001
6 Diastolic Blood Pressure 87.77 83.70 4.07 0.068