Table 4:

Effect of language preference, insurance status, and race/ethnicity on responsiveness of PF10a to changes in clinical disease activity

		Clinical Improvement (A 12-point decrease in CDAI)			Clinical Deterioration (A 12-point increase in CDAI)
		Change in PF10a score (β)	95% CI	P*	Change in PF10a score (β)	95% CI	P*
Model 2	Language
	English (Ref)	3.08	2.31, 3.86	NA	−2.92	−3.93, −1.92	NA
	Spanish	0.67	−1.37, 2.70	0.029	−0.83	−3.10, 1.44	0.098
	Chinese	1.84	−0.73, 4.42	0.363	−5.96	−8.61, −3.31	0.036
Model 3	Insurance
	Private (Ref)	3.63	2.59, 4.66	NA	−5.33	−6.74, −3.92	NA
	Medicare	2.21	1.17, 3.25	0.055	−1.62	−2.91, −0.34	<0.001
	Medicaid	0.70	−1.27, 2.67	0.005	−1.79	−3.80, 0.22	0.005
Model 4	Race/Ethnicity
	White (Ref)	3.41	2.37, 4.44	NA	−2.96	−4.41, −1.51	NA
	African American	2.47	−0.17, 5.12	0.520	−0.77	−4.36, 2.82	0.268
	Hispanic/Latino	2.79	−0.24, 5.82	0.708	−2.81	−5.99, 0.37	0.934
	Asian	1.50	−0.12, 3.14	0.052	−3.49	−5.15, −1.82	0.636
	Other	2.36	0.95, 3.78	0.241	−2.92	−4.74, −1.09	0.974

Data source: Longitudinal cohort (N=341, Encounters=1546)

CDAI: Clinical disease activity index; CI: Confidence interval; Ref: Reference category

Results are from the linear mixed effects regression and adjusted for baseline PF10a, and time; Model 2 incorporates an interaction term between changes in CDAI score (from previous visit) and preferred language; Model 3 incorporates an interaction term between changes in CDAI score and insurance status; Model 4 incorporates an interaction term between changes in CDAI score and race/ethnicity; β represents magnitude of change in PF10a score; P* is the p-value for statistical significance of effect modification by non-English language, non-Private insurance or non-white race.