Fig. 10.

Vasculature tracking of two control groups, characterized by OR-PAM and photograph at different days. The vasculature conditions were monitored at Pre-PDT, and post condition at day 1 and day 2 when usually the strongest injuries occur. Control group 1 was treated with PDT light (690 nm) without PS. Control group 2 was treated with PS without 690 nm irradiation. Photoacoustic imaging light (532 nm) was applied to mice in both control groups and PDT treatment groups, thus control group 1 is to evaluate the vascular injuries from light alone (PDT light 690 nm and photoacoustic light 532 nm), and control group 2 is to assess the PDT effect caused by the photoacoustic light at 532 nm.