Table 1. Experimental arrangement of different groups and corresponding observing periods.
Group | BPD (mg/kg) | F a (mW/cm2) | △t b | D c (J/cm2) | No. of animals |
||
---|---|---|---|---|---|---|---|
Pre+5 days Post | Pre+2 days Post | Pre+15 days Post | |||||
PDT 1 | 0.75 | 47 | 40 min | 113 | 1 | 1 | 1 |
PDT 2 | 0.75 | 126 | 15 min | 113 | 1 | 1 | 1 |
PDT 3 | 0.75 | 314 | 6 min | 113 | 1 | 1 | 1 |
PDT 4 | 0.75 | 876 | 2 min9s | 113 | 1 | 1 | 1 |
Control 1 | N/A | 47 | 40 min | 113 | NA | 1 | NA |
Control 2 | 0.75 | N/A | N/A | N/A | NA | 1 | NA |
F, fluence rate on the surface of targets, measured from the fiber output and then multiplied by an approximate factor of 0.74, to account for the light attenuation in ultrasonic coupling agent and the light blocked by the round tape boundary, as shown in Fig. 3(d).
△t, treatment time;
D, total light dose.