Figure 4.

The DNA damage levels in the lung, liver, and kidney of rats after Nano-TiO₂ treatment. (A and B): The OTM value and Tail DNA% value changed in the lung after Nano-TiO₂ treatment at different times. (C and D) The OTM value and Tail DNA% value changed in the liver after Nano-TiO₂ treatment at different times. (E and F) The OTM value and Tail DNA% value changed in the lung after Nano-TiO₂ treatment at different times. (G) Representative images of DNA damage in the lung of rats after Nano-TiO₂ treatment for 7 days (400x). (G₁: control group; G₂: 0.2 g/kg Nano-TiO₂ treatment group; G₃: 1 g/kg Nano-TiO₂ treatment group). The result was the average of at least three independent experiments. N=5, *P<0.05: day 1 in comparison to the control group; ^#P<0.05: day 3 in comparison to the control group; ^○P<0.05: day 7 in comparison to the control group.