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. 2020 Aug 27;135(1):329–339. doi: 10.1007/s00414-020-02406-w

Table 3.

Summary of microscopical findings

Organ Case 1
79-year-old woman
Case 2
27-year-old man
Case 3
70-year-old man
Lungs

-Rupture of intra-alveolar septum

-Pneumocyte detachment

-Hyaline membrane formation

-Fibrin deposits in the alveolar spaces

-Type II pneumocyte hyperplasia

-Focal type II pneumocytes with cytopathic changes

-Multinucleated giant cell-like pneumocyte aggregates

-Focal areas of rich neutrophilic infiltration

-Scattered areas of interstitial lymphocytic inflammatory infiltration

-Destruction of the alveolar wall lining

-Focal presence of hyaline membranes

-Intra-alveolar hemorrhage

-Large numbers of hemosiderin-laden macrophages within the alveolar space

-Mild pneumocyte hyperplasia

-Focal type II pneumocytes with cytopathic changes

-Multinucleated giant cell-like pneumocyte aggregates

-Interstitial, perivascular and peribronchial lymphocytic inflammatory infiltration

-Mild vasculitic reaction in some vessel walls

-Focal areas of rich neutrophilic infiltration

-Microthrombi of the small vessels

-Detachment of the alveolar lining with scattered pneumocytes within the alveolar space

-Moderate type II pneumocyte hyperplasia

-Focal type II pneumocytes with cytopathic changes

-Mild to moderate lymphocytic inflammatory reaction, more expressed in the perivascular region

-Mild vasculitic reaction in some vessel walls

-Microthrombi of the small vessels

Heart

-Mild to moderate perivascular edema vascular congestion

-Areas of small contraction band-like lesions

-Small number of scattered lymphocytes between the myocardial fibers

-Small vessel thrombosis

-Marked vascular congestion

-Mild edema between the muscle fibers

-Myocardial fibers that tend to form contraction bands

-Myocardosclerosis

-Old myocardial infarction

-Mild edema

-Marked vascular congestion

-Acute circulatory disorders

Kidneys

-Focal microthrombi formation within the glomerular capillary lumen

-Small areas of acute tubular injury with coagulative necrosis

-Shrunken glomeruli with enlarged Bowman space

-Acute tubular necrosis

Liver

-Centrilobular vascular congestion

-Macro-vesicular steatosis

-Periportal fibrosis with focal porto-portal and porto-central bridging fibrosis

-Mild to moderate lymphocytic infiltrate contained within the portal tract

-Regenerative nodules porto-portal bridging fibrosis

-Scattered lymphocytes within the portal areas

Spleen -Marked congestion white pulp atrophy absence of lymphoid follicles -Marked congestion white pulp atrophy absence of lymphoid follicles