Table 4.
Associations of clinical baseline factors with each response measure at follow-up (univariable logistic regression analyses)
| ASAS 20 response |
ASAS 40 response |
ASDAS ≥1.1 reduction |
ASDAS score <2.1 |
||||||
|---|---|---|---|---|---|---|---|---|---|
| Baseline variables | OR | (95% CI) | OR | (95% CI) | OR | (95% CI) | OR | (95% CI) | |
| Disease criteria | mNY | Ref | Ref | Ref | Ref | ||||
| ASAS imaging | 1.05 | (0.67, 1.66) | 1.16 | (0.72, 1.88) | 1.11 | (0.66, 1.86) | 0.89 | (0.50, 1.56) | |
| ASAS clinical | 1.09 | (0.35, 3.35) | 1.35 | (0.42, 4.27) | 1.19 | (0.33, 4.26) | 1.84 | (0.51, 6.62) | |
| Heel enthesitis | Yes vs no | 1.29 | (0.65, 2.56) | 1.37 | (0.69, 2.75) | 2.69 | (1.17, 6.20) | 1.18 | (0.51, 2.73) |
| Uveitis | Yes vs no | 1.53 | (0.91, 2.56) | 1.37 | (0.81, 2.32) | 1.49 | (0.83, 2.67) | 1.15 | (0.62, 2.12) |
| Dactylitis | Yes vs no | 2.08 | (0.71, 6.12) | 1.62 | (0.59, 4.46) | 2.15 | (0.70, 6.61) | 1.63 | (0.53, 5.01) |
| Psoriasis | Yes vs no | 1.20 | (0.57, 2.49) | 0.91 | (0.42, 2.003) | 0.69 | (0.30, 1.59) | 0.80 | (0.33, 1.93) |
| IBD | Yes vs no | 0.80 | (0.41, 1.58) | 0.60 | (0.27, 1.31) | 0.42 | (0.18, 0.99) | 0.76 | (0.32, 1.81) |
| Peripheral joint disease | Yes vs no | 0.63 | (0.37, 1.06) | 0.64 | (0.36, 1.14) | 0.83 | (0.46, 1.05) | 0.87 | (0.46, 1.67) |
| CRP (mg/dl) | Per unit increase | 0.99 | (0.99, 1.01) | 1.002 | (0.99, 1.01) | 1.004 | (0.99, 1.02) | 0.99 | (0.97, 1.01) |
| Tender joint count | Per unit increase | 0.97 | (0.92, 1.02) | 0.98 | (0.93, 1.04) | 1.003 | (0.95, 1.06) | 0.98 | (0.92, 1.05) |
| Swollen joint count | Per unit increase | 0.96 | (0.87, 1.06) | 0.94 | (0.82, 1.08) | 0.97 | (0.88, 1.08) | 0.93 | (0.79, 1.08) |
| BMI (per kg/m2) | Per unit increase | 0.95 | (0.91, 0.99) | 0.95 | (0.90, 0.99) | 0.97 | (0.92, 1.02) | 0.94 | (0.89, 1.001) |
| BASMI | Per unit increase | 0.80 | (0.70, 0.92) | 0.85 | (0.73, 0.99) | 0.92 | (0.80, 1.07) | 0.83 | (0.70, 0.99) |
| Comorbidity count | Per unit increase | 0.65 | (0.50, 0.84) | 0.57 | (0.42, 0.79) | 0.60 | (0.44, 0.82) | 0.51 | (0.35, 0.75) |
Italics indicate variable eligible for stepwise model (P <0.2).
OR: odds ratio; ref: reference category; ASAS: assessment in ankylosing spondylitis; ASDAS: ankylosing spondylitis disease activity score; BASMI: Bath ankylosing spondylitis metrology index.