Fig. 1.

Proportions of B-cell subsets in HCs, iSLE patients and SLE patients

Medians and IQR are depicted for every group. Proportions of transitional B-cells (A), naïve B-cells (B), plasma blasts/plasma cells (C), memory B-cells (D) and IgD-only memory B-cells (G) were not different between all groups. Switched memory B-cells were elevated in SLE patients compared with HCs (E). Non-switched memory B-cells were decreased in SLE patients compared with HCs and iSLE patients (F). ABCs were elevated in iSLE and SLE patients compared with HCs (H). *P < 0.05, **P < 0.01. HCs: healthy controls; iSLE: incomplete SLE; IQR: interquartile range; ABCs: age-associated B-cells.