Table 3.
Mean scores of digit span, word fluency, trail making test A, and trail making test B from baseline to week 8 in the participants with major depressive disorder without atypical features
| Buspirone augmentation (N=22) |
p of paired t test | Non-buspirone (N=19) |
p of paired t test | |||
|---|---|---|---|---|---|---|
| Mean (SD) | Mean (SD) change | Mean (SD) | Mean (SD) change | |||
| Digit span | ||||||
| Baseline | 16.00 (3.31) | 17.34 (4.57) | ||||
| Week 8 | 18.714 (3.17) | 2.71 (2.27) | 0.001* | 18.19 (4.83) | 0.84 (1.98) | 0.109 |
| Word fluency | ||||||
| Baseline | 15.93 (3.52) | 19.06 (6.97) | ||||
| Week 8 | 19.14 (5.16) | 3.21 (3.56) | 0.005* | 23.24 (6.56) | 4.18 (4.85) | 0.003* |
| Trail making test A | ||||||
| Baseline | 40.43 (24.51) | 43.24 (20.50) | ||||
| Week 8 | 32.93 (12.83) | -7.50 (19.74) | 0.179 | 38.29 (19.62) | -3.94 (9.09) | 0.093 |
| Trail making test B | ||||||
| Baseline | 69.22 (28.82) | 110.31 (75.32) | ||||
| Week 8 | 73.22 (30.30) | 4.00 (16.84) | 0.496 | 100.81 (68.79) | -9.50 (28.91) | 0.208 |
Data represent mean [standard deviation (SD)].
*
p<0.05