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. 2020 Aug 1;10(21):9721–9740. doi: 10.7150/thno.44342

Figure 3.

Figure 3

Knockdown of AURKB decreases tumor growth in a xenograft mouse model. (A) Tumors from the A375 and A375R xenograft models. (B) Tumor size in each group was measured every week and tumor weight was measured at day 22. (C) The expression of PCNA in A375 and A375R tumors in the xenograft model was detected by immunohistochemistry staining; the scale bar = 100 µm. (D) Tumors from M249 and M249R xenograft models. (E) Tumor size in each group was measured every week and tumor weight was measured at day 22. (F) The expression of PCNA in M249 and M249R tumors from the xenograft model was detected by using immunohistochemistry staining; the scale bar = 100 µm. Statistical significance was determined by one-way ANOVA. The asterisks indicate a significant difference compared with the shcontrol group (***, p < 0.001).