Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
PAK1 in autophagy pathways. PAK1 regulates autophagy via direct or indirect regulation. Acetylation of PAK1 could phosphorylate ATG5 to inhibit its ubiquitination-dependent degradation to promote autophagy. In addition, PAK1-AKT-mTOR signaling is another key pathway that involved in PAK1-regulated autophagy. Moreover, PAK1-mediated autophagy-related genes expression is also contribute to autophagy regulation.
