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. 2020 Aug 1;10(21):9741–9766. doi: 10.7150/thno.46913

Figure 9.

Figure 9

The crosstalk between PAK1 and other cancer-related pathways. PAK1 can also regulate the proliferation and cytoskeletal movement of cancer cells via crosstalk with the Hippo-YAP signaling pathway and the TGF-β signaling pathway. In addition, PAK1 can promote tumorigenesis and angiogenesis through Notch and STAT5 signaling pathways activation.