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. 2020 Aug 2;10(21):9865–9887. doi: 10.7150/thno.46771

Figure 11.

Figure 11

Typical images of HepG2 tumor-bearing mice at predetermined time intervals after injection of Saline, MnMSN, Free SFB, MnMSN@SFB, or FaPEG-MnMSN@SFB at a SFB-equivalent dose of 10 mg/kg (A). The tumor volume changes (B), body weight changes (C) and Kaplan-Meier survival curves (D) of nude mice in each group during the treatment period (n=6). The intratumoral GSH (E) and GPx4 (F) levels after various treatment. The H&E, Ki67 and TUNEL staining images of tumor tissues indicating the tissue necrosis, cell proliferation and cell apoptosis (G), scale bar is 100 µm.